PLEASE HELP How to remove a trojan virus (downloader)?

My antivirus software (Trend Micro for Internet security) is to date, but not clean, delete or quarantine the virus. Microsoft Deleter malware does not work. Windows Defender does not work on it and not let me delete file physically well. I need to know how to destroy this virus, because it keeps opening pages and slowing down my computer. Besides, I do not I have nothing screwing with my files because the year 12 of the instant messaging company yet. PLEASE HELP

Do not panic. First, using another PC to download anti-virus ClamWin Portable ClamWin Portable and installed on a USB stick. Download here http://portableapps.com/apps/utilities/clamwin_portable After installation, commissioning Clamwin anti-virus in USB pen drive and update the latest definition files against viruses. Select the menu bar tool, set the preferences to remove virus. Document on how to configure ClamWin When the module http://support.real-time.com/open-source/clamwin/index.html USB memory is ready for use. Start the infected PC in safe mode by pressing F8 during startup. Clamwin Run Anti-virus is installed on USB pen drive to scan your PC infected.

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